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N., Ock S

The investigators attributed the angiogenic effect to upregulation of vascular endothelial growth factor receptor 2 (VEGFR2) and activation of the Aktendothelial nitric oxide synthase (eNOS) signaling pathway

Administered intraperitoneally in doses ranging from 5 to 150 g/kg, GHK-Cu demonstrated significant pain relief and reduction in aggressive behavior in a foot-shock model

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- Kelleyene P

We acknowledge, however, that the ex vivo gut segment incubations have the inherent limitation of not being subject to neuro-endocrine inputs, nor the dynamic metabolism of the intact GI tract within a host